Straticyte™ can provide your doctor with a more accurate assessment of your oral lesion

An oral precancer lesion may appear as a red or white spot in the mouth. This lesion may not have any symptoms and might only be detected by the patient or dentist during a routine examination. Identification of the white or red spot as precancer requires a biopsy (removing a sample of the lesion) and examination of the tissue by a pathologist.

Straticyte™ provides your healthcare professional with more accurate information about your lesion; is it cancer, is the lesion precancer, and how likely the lesion will progress to become an oral cancer. This information will assist your healthcare professional in recommending appropriate next steps, including when follow-up should occur and a treatment plan, if needed.

Oral cancer often requires major surgery, and may severely impact your quality of life and even lead to death. Early detection is critical because oral cancer, at a late stage, is much harder to treat.

Oral Lesions:

Lichen Planus

  • Common disorder
  • Multiple presentations
  • Less than 2% may become malignant over a 10 year period
  • Necessary to distinguish from lichenoid dysplasia
Leukoplakia

  • Leukoplakia is white plaque that cannot be scraped off, cannot be given another specific diagnosis and has no known cause (except tobacco use)
  • 7 to 15% show dysplasia or a malignant tumor on biopsy
  • Varying patterns, granular, wart like, thick, thin
Erythroleukoplakia

  • This is an abnormal patch of red and white tissue that forms on mucous membranes in the mouth and may become cancer.
  • Tobacco (smoking and chewing) and alcohol may increase the risk of erythroleukoplakia.
Erythroplakia

  • Erythroplakia is defined as a red patch
  • These may appear as smooth, velvety, granular or nodular lesions often with a well-defined margins
  • The soft palate, the floor of mouth, the undersurface of tongue are the most common sites
  • More common among middle aged to elderly persons and, especially among men
Actinic Cheilitis

  • Effect of direct exposure to sunlight over a prolonged period of time
  • Found primarily on the lower lip
  • Common in outdoor workers, sun worshippers
  • Deceptively benign in appearance, both clinically and histologically
Sublingual Keratosis

  • Uncommon form of “leukoplakia”
  • Thick white patch on the undersurface of the tongue or floor of mouth
  • Initial biopsy is often benign
  • High incidence of cancer
Proliferative Verrucous Leukoplakia (PAL)

  • PAL is an uncommon form of progressive multifocal leukoplakia and has a high rate of malignant transformation to either squamous cell cancer or verrucous carcinoma
  • PAL has a high probability of recurrence.
  • More often seen in females
  • Age range is 20-80
  • Lining of the cheeks, floor of the mouth and tongue are often most affected
  • 70% of patients will develop a cancer within a decade following diagnosis
Stomatitis in Reverse Smokers

  • This is caused by extreme heat and tobacco in the mouth, most commonly from inserting the lit end in the mouth
  • This is a common practice in parts of India, South America and the Philippines
  • Older women are most often affected
  • Differs from nicotinic stomatitis
  • Accounts for 50% of malignancies in some parts of the world

Oral cancer often appears as a spot, growth or lesion in your mouth that won’t heal.

Other things to look for:

  • Dark red or white patches in the mouth
  • Lumps on lips, tongue or neck
  • Unexplained bleeding in the mouth
  • Sore throat and difficulty swallowing

The growth or lesion may not cause you any problems, other than being visible. However, it is still potentially dangerous.

Oral Cancer Statistics

If not detected and treated early, oral cancers can be life threatening and even lead to death.
  • Consider oral cancer has:
  • 50% mortality rate within five years
  • One death every hour in North America
  • 450,000 new cases worldwide each year
  • Early detection of oral cancer has an 80% survival rate 80% 80%

Talk to your Healthcare Professional

Please talk to your Healthcare Professional if you have any questions about Straticyte™ and your oral lesion.